RNA Details
Disease Name
cardiac senescence
Tissue
heart
RNA Symbol
circ-Foxo3
RNA ID
RNA Type
circRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR
Target
Foxo3
Pathway
NA
PubMed ID
Title
Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses
Year
2017
Function
We also found that silencing circ-Foxo3 inhibited senescence of mouse embryonic fibroblasts and that ectopic expression of circ-Foxo3 induced senescence.